Table 2 Correlation between combined FOXP3+ T-reg and B7-H1 with the clinicopathological parameters of 62 breast cancer patients
FOXP3 and B7-H1 Expression | *P | |||
|---|---|---|---|---|
Both + | One + | Both - | ||
Age | ||||
< 40 years | 21 (55)♣ | 7 (18) | 10 (26) | 0.496 |
≥ 40 years | 10 (45) | 7 (32) | 5 (23) | |
Tumor Size | ||||
<4 cm | 18 (64) | 6 (21) | 4 (14) | 0.128 |
≥ 4 cm | 13 (41) | 8 (25) | 11 (34) | |
â—† Lymph Node Metastasis | ||||
Negative | 12 (63) | 3 (16) | 4 (21) | 0.605 |
1 to 3 | 4 (33) | 3 (25) | 5 (42) | |
4 to 9 | 9 (50) | 5 (28) | 4 (22) | |
10 or more | 5 (56) | 3 (33) | 1 (11) | |
Histological Grade (SBR) | ||||
II | 9 (30) | 7 (23) | 14 (47) | <0.001 |
III | 22 (73) | 7 (23) | 1 (3) | |
Lymphovascular Invasion | ||||
Positive | 20 (56) | 8 (22) | 8 (2) | 0.745 |
Negative | 11 (46) | 6 (25) | 7 (29) | |
Her2/neu Status | ||||
Positive | 16 (57) | 7 (25) | 5 (18) | 0.487 |
Negative | 15 (47) | 7 (22) | 10 (31) | |
ER Status | ||||
Positive | 16 (40) | 10 (25) | 14 (35) | 0.017 |
Negative | 15 (75) | 4 (20) | 1 (5) | |
PR Status | ||||
Positive | 11 (38) | 7 (24) | 11 (38) | 0.054 |
Negative | 20 (65) | 7 (23) | 4 (13) | |
Neo-adjuvant Chemotherapy | ||||
With | 17 (49) | 9 (26) | 9 (26) | 0.828 |
Without | 14 (56) | 5 (20) | 6 (24) | |
Lymphocyte Infiltration | ||||
Focal | 10 (38) | 5 (19) | 11 (42) | 0.022 |
Moderate | 9 (47) | 7 (37) | 3 (16) | |
Severe | 12 (80) | 2 (13) | 1 (7) | |