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Table 3 Protein levels which characterized advanced PDAC stage

From: Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis

  Number of specimens (%)  
Marker Low protein level High protein level p-value
  I II III IV I II III IV  
Cytoplasm
PTEN 1 (7) 8 (53) 6 (40) 0 1 (9) 0 8 (73) 2 (18) 0.01
βCAT 1 (6) 8 (50) 5 (31) 2 (13) 0 1 (10) 9 (90) 0 0.04
p-NFκB 1 (5) 9 (47) 7 (37) 2(11) 0 0 5 (100) 0 0.05
Nucleus          
Y705p-STAT3 0 0 6 (75) 2 (25) 1 (6) 9 (50) 8 (44) 0 0.01
p-GSK3β 1 (5) 9 (45) 8 (40) 2 (10) 0 0 6 (100) 0 0.05
  1. Listed are tumors of stage I to IV, and their proportions (%) in low/high protein levels. Advanced PDAC stage (III and IV) associated with high protein levels (PTEN, βCAT, p-NFκB and p-GSK3β) and low p-STAT3 levels (Fisher's exact test, p ≤ 0.05).