Skip to main content
Figure 4 | BMC Cancer

Figure 4

From: Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis

Figure 4

Ductal epithelia and the pancreas parenchyma. (A) The profile of six proteins shows significant differences in mean protein levels in ducts of normal pancreas in PDAC compared with ducts in non-PDAC: PKBβ (p = 0.03), nuclear (N-) p-GSK3β (p = 0.008), EGFR (p = 0.055), N-p-ERK (p = 0.04), N-p-p38 (p = 0.03) and p-S6 (p = 0.03). (B) A representative image of centroacinar cells (arrows) and larger ducts (arrowheads) shows positive staining for p-mTOR. (C) A subset of the signaling proteins shows differential staining among the cellular components of the pancreas.

Back to article page
\