Table 2
BAC ID | Chrom. region | Candidate Gene | Frequency of DCNAs(%) | Frequency of DCNAs(%) | P-value* |
|---|---|---|---|---|---|
Gain | |||||
Node metastasis | Positive (n = 60) | Negative (n = 23) | |||
225 | 2q24.32 | TMEM132D | 3 | 26 | 0.0005 |
1308 | 5q13.2 | FCHO2, MGC13034 | 7 | 43 | 0.0005 |
491 | 16p13.11 | PKD1P3 | 5 | 35 | 0.0006 |
884 | 19q13.32 | N.i. | 5 | 30 | 0.0006 |
Liver metastasis | Positive (n = 6) | Negative (n = 77) | |||
1322 | 1p13.2 | CHIA, C1orf88, OVGP1 | 43 | 3 | <0.0001 |
1271 | 8p22 | N.i. | 67 | 13 | 0.0016 |
92 | 11p15 | ST5 | 43 | 6 | 0.0006 |
Peritoneal dissemination | Positive (n = 19) | Negative (n = 64) | |||
948 | 15q22.1 | MYO1E, LDHAL6B | 22 | 0 | 0.0002 |
155 | Xp21.2 | XK | 35 | 5 | 0.0009 |
Histologic type | Diffuse (n = 42) | Intestinal (n = 41) | |||
563 | 10p15.3 | DIP2C | 7 | 38 | 0.0011 |
911 | 10q24.2 | SPFH1, CHUK, CWF19L1 | 0 | 23 | 0.0013 |
Loss | |||||
Node metastasis | Positive (n = 60) | Negative (n = 23) | |||
936 | 8p21.2 | DOCK5, GNRH1, KCTD9, CDCA2 | 3 | 23 | 0.0023 |
1158 | 8p21.1 | EXTL3 | 3 | 21 | 0.0023 |
878 | 13q31.2 | SLITRK5 | 13 | 47 | 0.0007 |
Liver metastasis | Positive (n = 6) | Negative (n = 77) | |||
877 | 1p32.3 | LRP8, | 50 | 5 | 0.0006 |
1386 | 7q35 | CNTNAP2, | 43 | 4 | 0.0001 |
309 | 21q22.3 | HSF2BP, KIAA0179, | 29 | 1 | 0.0002 |
Peritoneal dissemination | Positive (n = 19) | Negative (n = 64) | |||
1407 | 3p26.3 | CNTN6 | 33 | 6 | 0.0009 |
503 | 3p24.3 | UBE2E1 | 32 | 6 | 0.0009 |
229 | 4q31.1 | MAML3 | 44 | 5 | <0.0001 |
Histologic type | Diffuse (n = 42) | Intestinal (n = 41) | |||
1292 | 4q34.1 | N.i. | 17 | 53 | 0.0004 |
1393 | 5q33.2 | TIMD4 | 15 | 48 | 0.0007 |
91 | 8p21.3 | INTS10 | 0 | 24 | 0.0006 |
227 | 14q32.33 | IGHV3-22 | 16 | 54 | 0.0001 |
1122 | 15q15.3 | GANC, CAPN3 | 2 | 27 | 0.0003 |
1210 | 17q13.2 | ATP2A3, ZZEF1 | 5 | 41 | 0.0001 |