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Figure 1 | BMC Cancer

Figure 1

From: Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients

Figure 1

Cells of a healthy (cancer free) individual (case K2) heterozygous for the large CEN15 marker (derived from the paternal parent) after two-color FISH with SNRPN (red signals) and CEN15 (green signals). Left, two interphase cells representing SD cells for SNRPN and SS cells for CEN15. Right, cell at metaphase with chromosome-15 homologues identified by the CEN15 and SNRPN signals. Note the difference in signal size between the two CEN15 counterparts in each cell, and the association of the replicated SNRPN locus (doublet; D-signal) in both interphase cells with the large CEN15.

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BMC Cancer

ISSN: 1471-2407

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