Skip to main content

Table 1 Allelic frequencies comparison between cases and controls in the four SNPs tested, in both BC and MM pathologies

From: Genetic analysis of the vitamin D receptor gene in two epithelial cancers: melanoma and breast cancer case-control studies

    

BREAST CANCER

MELANOMA

HapMap

 

Other names

SNP

Nucleotide

Cases (N = 549)

Controls (N = 556)

 

Cases (N = 283)

Controls (N = 245)

 

Caucasian

SNP ID

 

Location

Change*

MAF

MAF

p-value++

MAF

MAF

p-value++

MAF

rs4516035

 

5' upstrem

T > C

0.41

0.39

0.27

0.44

0.40

0.28

0.45

rs2228570

FokI. rs10735810

Met1Thr

G > A

0.37

0.34

0.08

0.31

0.33

0.33

0.44

rs731236

TaqI

Ile352

T > C

0.38

0.43

0.028

0.41

0.39

0.50

0.44

rs739837

BglI

3' utr

T > G

0.46

0.46

0.90

0.47

0.50

0.74

0.43

  1. MAF, Minor Allele Frequency.
  2. Statistically significant results (p < 0.05) indicated in bold.
  3. * Correspondence of nomenclature of SNP alleles are as following: the FokI alleles G and A correspond to F and f, respectively; the TaqI alleles T and C
  4. correspond to T and t, respectively; and BglI alleles T and G correspond to B and b, respectively.
  5. ++p-value, difference of MAF between cases and controls.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us