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Table 1 Allelic frequencies comparison between cases and controls in the four SNPs tested, in both BC and MM pathologies

From: Genetic analysis of the vitamin D receptor gene in two epithelial cancers: melanoma and breast cancer case-control studies

     BREAST CANCER MELANOMA HapMap
  Other names SNP Nucleotide Cases (N = 549) Controls (N = 556)   Cases (N = 283) Controls (N = 245)   Caucasian
SNP ID   Location Change* MAF MAF p-value++ MAF MAF p-value++ MAF
rs4516035   5' upstrem T > C 0.41 0.39 0.27 0.44 0.40 0.28 0.45
rs2228570 FokI. rs10735810 Met1Thr G > A 0.37 0.34 0.08 0.31 0.33 0.33 0.44
rs731236 TaqI Ile352 T > C 0.38 0.43 0.028 0.41 0.39 0.50 0.44
rs739837 BglI 3' utr T > G 0.46 0.46 0.90 0.47 0.50 0.74 0.43
  1. MAF, Minor Allele Frequency.
  2. Statistically significant results (p < 0.05) indicated in bold.
  3. * Correspondence of nomenclature of SNP alleles are as following: the FokI alleles G and A correspond to F and f, respectively; the TaqI alleles T and C
  4. correspond to T and t, respectively; and BglI alleles T and G correspond to B and b, respectively.
  5. ++p-value, difference of MAF between cases and controls.