Figure 5

Heatmap illustrating the expression level of the twelve transcription factors (rows) found in the four signalling pathways: FGF, p38 MAPK, cAMP and calcium. The columns contain expression of the 15 patients without CIS, 13 patients with adjacent CIS and 23 patients with muscle invasive bladder carcinoma, mTCC. Up regulated genes are yellow, down regulated genes are blue, while black indicates no change with no CIS samples as reference. The colour bar indicates the clinical diagnosis, green, CIS; orange, no CIS, gray, muscle invasive tumors.