Table 5 Comparative analysis between genotype frequencies and the risk of lung cancer in the subgroups of non-drinkers
From: The genetic polymorphisms of HER-2 and the risk of lung cancer in a Korean population
Non-drinker | Genotype | Cases (n = 118) | Controls (n = 78) | OR (95% CI) | p-value | asOR (95% CI)b | p-value |
|---|---|---|---|---|---|---|---|
-3444 C>T | CC | 38 | 23 | 1 | Â | 1 | Â |
|  | CT | 51 | 47 | 0.66 (0.34 – 1.26) | 0.21 | 0.69 (0.35 – 1.35) | 0.28 |
|  | TT | 29 | 8 | 2.19 (0.86 – 5.61) | 0.10 | 2.85 (1.06 – 7.69) | 0.04 |
|  | CT+TT | 80 | 55 | 0.88 (0.47 – 1.64) | 0.69 | 0.96 (0.51 – 1.82) | 0.90 |
| Â | CC+CT | 89 | 70 | 1 | Â | 1 | Â |
|  | TT | 29 | 8 | 2.85 (1.23 – 6.62) | 0.01 | 3.60 (1.47 – 8.84) | 0.01 |
-1985 G>T | GG | 39 | 23 | 1 | Â | 1 | Â |
|  | GT | 50 | 47 | 0.63 (0.33 – 1.20) | 0.16 | 0.67 (0.34 – 1.31) | 0.24 |
|  | TT | 29 | 8 | 2.14 (0.84 – 5.46) | 0.11 | 2.81 (1.04 – 7.56) | 0.04 |
|  | GT+TT | 79 | 55 | 0.85 (0.46 – 1.57) | 0.60 | 0.94 (0.50 – 1.78) | 0.85 |
| Â | GG+GT | 89 | 70 | 1 | Â | 1 | Â |
|  | TT | 29 | 8 | 2.85 (1.23 – 6.62) | 0.01 | 3.60 (1.47 – 8.84) | 0.01 |
P1170A C>G | CC | 40 | 22 | 1 | Â | 1 | Â |
|  | CG | 50 | 48 | 0.57 (0.30 – 1.10) | 0.10 | 0.61 (0.31 – 1.21) | 0.16 |
|  | GG | 28 | 8 | 1.93 (0.75 – 4.94) | 0.17 | 2.64 (0.97 – 7.18) | 0.06 |
|  | CG+GG | 78 | 56 | 0.77 (0.41 – 1.43) | 0.40 | 0.86 (0.45 – 1.63) | 0.64 |
| Â | CC+CG | 90 | 70 | 1 | Â | 1 | Â |
|  | GG | 28 | 8 | 2.72 (1.17 – 6.34) | 0.02 | 3.59 (1.46 – 8.88) | 0.01 |