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Table 1 Breast tissue specimens used in the study

From: Gene expression variation between distinct areas of breast cancer measured from paraffin-embedded tissue cores

Patient No.

Histological grade

IHC

Block

No. of layers

No. of tissue cores1

  

ER

PgR

Her2

Ki-67 LI (%)

  

IDC

DCIS

N

1

3

+

+

-

70

1.1

2

3/3

1/1

1/1

2

2

+

+

-

n.d.

2.1

3

2/2

1/1

1/1

3

3

+

+

+

50

3.1

2

3/3

1/1

0/12

4

2

+

-

+

30

4.1

3

3/3

1/1

1/1

      

4.2

3

 

1/1

 
      

4.3

3

  

0/13

5

2

+

+

+

5

5.1

3

2/2

  
      

5.2

2

 

1/1

0/13

      

5.3

1

0/14

0/13

0/14

      

5.4

2

  

1/1

6

3

-

-

+

80

6.1

3

1/22

1/1

0/22

      

6.2

3

 

1/24

 
      

6.3

3

 

0/14

 
      

6.4

3

  

1/22

7

2

+

+

-

10

7.1

3

2/34

  
      

7.2

1

  

1/24

  1. IHC = immunohistochemistry; ER = estrogen receptor; PgR = progesteron receptor; Her2 = Her2/neu; Ki-67 LI = Ki-67 labeling index; N = normal tissue; n.d. = not determined; 1 = number of tissue cores analyzed/total number of tissue cores punched; 2 = tissue cores excluded from gene expression measurement due to insufficient RNA yield; 3 = tissue cores excluded from gene expression measurement due to insufficient RNA quality; 4 = tissue cores excluded from gene expression measurement due to inappropriate localization of the core.
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BMC Cancer

ISSN: 1471-2407

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