Skip to main content
Figure 4 | BMC Cancer

Figure 4

From: Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors

Figure 4

Expression of proteases in IEC-6 cell populations transduced with activated MEK isoforms. (A) Expression of MMP-13 was analyzed by immunoblotting. Induction of MMP activity was analyzed by zymography on acrylamide gels co-polymerized with casein (MMP-3/10) or gelatin (MMP2 and MMP9) substrates. Photographs of the gels are shown. (B) Quantitative PCR analysis of urokinase receptor mRNA levels. Expression levels are expressed as fold-increase relative to vector-infected cells.

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us