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Table 4 Distribution of ESR1 four-locus haplotype frequencies as estimated through EM algorithms among endometrial cancer cases and population controls

From: Estrogen receptor alpha gene polymorphism and endometrial cancer risk – a case-control study

Locus

Proportion estimated to carry haplotype

rs2234693

rs9340799

rs4986934

rs1801132

Controls (n = 1560)

All cases

(n = 694)

Endometroid cases

(n = 647)

T

A

C

C

0.371

0.404

0.406

C

G

C

C

0.288

0.255

0.252

C

A

C

C

0.114

0.118

0.118

T

A

C

G

0.123

0.137

0.135

C

G

C

G

0.055

0.045

0.046

T

A

T

G

0.028

0.025

0.027

Proportion accounted for by the most common haplotypes:

0.979

0.984

0.984