Skip to main content

Table 3 Odds ratios (OR) for endometrial cancer and 95% confidence intervals (CI)

From: Estrogen receptor alpha gene polymorphism and endometrial cancer risk – a case-control study

    Marker rs2234670 rs2234693 rs9340799 rs4986934 rs1801132
Genotype 00a Case/controls   232/441 211/382 324/573 617/1276 406/834
   OR (CI)   1 (ref) 1 (ref) 1 (ref) 1 (ref) 1 (ref)
  01a Case/controls   307/618 336/670 280/632 44/89 226/468
   OR (CI) Univariateb 0.95 (0.75–1.19) 0.88 (0.70–1.11) 0.79 (0.64–0.98) 1.02 (0.68–1.54) 1.02 (0.82–1.26)
    Multivariatec 0.92 (0.72–1.16) 0.86 (0.68–1.10) 0.75 (0.60–0.93) 1.03 (0.67–1.58) 1.00 (0.80–1.26)
  11a Case/controls   123/309 115/316 58/163 1/3 30/66
   OR (CI) Univariateb 0.72 (0.54–0.97) 0.65 (0.48–0.87) 0.59 (0.41–0.85) 0.94 (0.09–9.40) 0.94 (0.58–1.51)
    Multivariatec 0.73 (0.54–0.99) 0.65 (0.48–0.89) 0.53 (0.37–0.77) 1.02 (0.09–11.61) 0.95 (0.58–1.57)
  1. Univariate results include individuals with complete information about the covariates used in the multivariate analysis.
  2. a The genotypes are rs2234670: 00 = ≤ 14/≤ 14, 01 = ≤ 14/> 14, 11 => 14/> 14; rs2234693: 00 = T/T, 01 = T/C, 11 = C/C; rs9340799: 00 = A/A, 01 = A/G, 11 = G/G; rs4986934: 00 = C/C, 01 = C/T, 11 = T/T; rs1801132: 00 = C/C, 01 = C/G, 11 = G/G. b Long-term users of menopausal hormones and diabetics were over-sampled, thus logistic regression models are conditioned for age- and sampling category, which means that only those with complete information about hormone use and diabetes mellitus were included. c Multivariate models are adjusted for parity (continuous), BMI (continuous), smoking (ever, never) and use of oral contraceptives (ever, never)