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Table 2 Distribution of endometrial cancer risk factors among participating endometrial cancer cases and population controls

From: Estrogen receptor alpha gene polymorphism and endometrial cancer risk – a case-control study

Co-variate Cases/controls Cases Controls  
  N Mean (SD) P value
Age 702/1563 64.1 (6.80) 63.4 (7.03) 0.0001
Age at menarche 653/1427 13.5 (1.37) 13.5 (1.42) 0.14
Age at last birth 604/1405 29.4 (5.08) 30.4 (5.34) 0.0002
Age at menopause 614/1503 51.0 (4.06) 50.1 (3.91) <0.0001
Recent BMI 701/1546 27.4 (5.31) 25.5 (4.27) <0.0001
   Percent  
Nulliparous 158/97 14 10  
1 childbirth 289/146 21 18 0.008
2+ childbirths 1116/459 65 71  
Family historya 667/1397 10 5 <0.0001
Diabetes Mellitus, self-reportedb 702/1441 10 8 0.17
Ever use of oral contraceptives 699/1550 24 36 <0.0001
Ever use of menopausal hormonesb 690/1541 28 28 0.97
Smokingc 702/1563 35 43 0.0004
  1. a Family history is defined as having a mother or a sister with endometrial cancer. bWomen with self-reported diabetes mellitus and those who had used menopausal hormones containing medium potency estrogens were over-sampled into the study and thus the proportions do not reflect known case-control differences c Smoking is defined as a participant having smoked at least 100 cigarettes during her lifetime or having smoked regularly for at least one year
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