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Table 2 Expected haplotype frequencies between Arg72Pro and PIN3 Ins16bp polymorphisms. Association with familial and sporadic breast cancer risk.

From: Importance of TP53 codon 72 and intron 3 duplication 16bppolymorphisms in prediction of susceptibility on breast cancer

Haplotypes Positive FH Cases Controls OR (95% CI) Negative FH Cases Controls OR (95% CI)
Arg-A1 0.607 0.711 Reference 0.695 0.705 Reference
Arg-A2 0.091 0.041 2.10 (1.08–4.06) 0.048 0.045 1.06 (0.53–2.12)
Pro-A1 0.150 0.111 1.49 (0.86–2.58) 0.098 0.119 0.80 (0.49–1.32)
Pro-A2 0.151 0.137 1.27 (0.72–2.24) 0.160 0.131 1.27 (0.83–1.95)
  1. FH – family history; OR – odds ratio; CI – confidence interval