Voluntary exercise inhibits intestinal tumorigenesis in Apc Min/+mice and azoxymethane/dextran sulfate sodium-treated mice

Table 3 Effect of voluntary exercise on small intestinal tumor or serum levels of PGE2 in Apc ^Min/+ mice^a

Group (N)	PGE2 levels (% decrease)
Experiment 1
Small intestinal tumors (ng/mg protein)
Control (11)	12.7 ± 1.4
Exercise (10)	8.8 ± 0.8^b	(31%)
Experiment 2
Serum (pg/ml)
Control (19)	436.4 ± 103.6
Exercise (19)	390.3 ± 111.7	(11%)
Small intestinal tumors (ng/mg protein)
Control (13)	26.5 ± 4.0
Exercise (13)	20.5 ± 2.4	(23%)

^aSamples from Experiments 1 and 2. PGE2 levels were determined in small intestinal tumor extracts and(or) serum samples by EIA. Values are mean ± SE of the number of samples (N) analyzed.
^bp ≤ 0.05, two-tailed t-test.

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