Table 5 Univariate Cox Regression Analysis of Factors Associated with Distant Disease-free Survival in the Triple-Negative Tumors
Variables | P value | Relative Risk of recurrence (95% CI) |
|---|---|---|
Size | Â | Â |
   ≤2 cm |  | 1.0 (reference) |
   >2 cm | 0.92 | 1.26 (0.44 to 3.65) |
Nodal status | Â | Â |
   Negative |  | 1.0 (reference) |
   Positive | 0.02 | 2.60 (1.14 to 6.96) |
Grade | Â | Â |
   1 |  | 1.0 (reference) |
   2, 3 | 0.22 | 2.46 (0.68 to 10.39) |
TP53 expression | Â | Â |
   Negative |  | 1.0 (reference) |
   Positive | 0.61 | 1.12 (0.72 to 1.77) |
Ki67 expression | Â | Â |
   Low |  | 1.0 (reference) |
   High | 0.55 | 0.88 (1.59 to 1.34) |
EGFR IHC | Â | Â |
   Negative |  | 1.0 (reference) |
   Positive | 0.88 | 1.07 (0.48 to 2.36) |
EGFR gene copy number | Â | Â |
   <3 |  | 1.0 (reference) |
   ≥3 | 0.2 | 0.27 (0.03 to 2.05) |
Cytokeratins | Â | Â |
   Negative |  | 1.0 (reference) |
   Positive | 0.42 | 0.72 (0.33 to 1.68) |
Basal like type | Â | Â |
   + |  | 1.0 (reference) |
   - | 0.67 | 0.79 (0.34 to 1.80) |