Figure 3
From: Reduced expression of N-Myc downstream-regulated gene 2 in human thyroid cancer
Reduced NDRG 2 and increased c- MYC mRNA level in thyroid cancers. (A) Real-time PCR was used to detect differences in NDRG2 and c-MYC RNA levels in thyroid tissues. The mean values of NDRG2 and c-MYC mRNA levels were calculated after normalization to the expression of GAPDH. The P values comparing the expression of NDRG2 and c-MYC between the thyroid cancer and the adjacent normal tissues were below 0.05. (B) Analysis of NDRG2 expression using the different histotypes and distant metastasis of thyroid cancer. There are four histotypes of thyroid cancers, including papillary carcinomas (PTC), follicular carcinomas (FTC), medullary carcinomas (MTC) and undifferentiated carcinomas (UTC). N in the bracket indicates the numbers of each histotype. There were six patients with distal metastases and 29 with no metastasis. p > 0.05.