Figure 2
From: Amplification of HER2 is a marker for global genomic instability
Detection of allelic imbalance in a HER2+ breast tumor with fluorescence-based genotyping. Alleles for marker D17S250 on chromosome 17q12 were detected as fluorescent peaks in reference DNA (top panel) and microdissected breast tumor DNA (bottom panel). A normalized peak height ratio of 0.28 was calculated for the tumor sample using the following peak heights in relative fluorescence units (rfu): tumor DNA – 8,791 rfu and 30,585 rfu, referent DNA – 61,195 rfu and 59,934 rfu.