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Figure 2 | BMC Cancer

Figure 2

From: Upregulated HSP27 in human breast cancer cells reduces Herceptin susceptibility by increasing Her2 protein stability

Figure 2

Identification of HSP27 overexpressed in SK-BR-3 HR. (a) Typical pattern of two-dimensional (2-DE) gel electrophoresis analysis of SK-BR-3 and SK-BR-3 HR cells. (b) Identification of HSP27 by MALDI-MS analysis. The protein spot indicated in the enlarged image in Figure 2A was in-gel-digested by trypsin and subjected to MALDI-MS analysis. The protein was identified as human HSP27. (c) Western-blot analysis to confirm overexpressed HSP27 in SK-BR-3 HR cells. (d) Subcellular levels of HSP27 and Her2 in seven individual human breast cancer cell lines.

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BMC Cancer

ISSN: 1471-2407

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