Figure 6
From: Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy
Cell differentiation and apoptosis. The levels of the neural marker βIII Tubulin and of the antiapoptotic protein Bcl2 were analyzed by western blot. The experiment was performed twice using two different cell extracts. a) The higher level of βIII Tubulin detected in knockdown (KD) vs control (Ctrl) indicates that Msi1 may play a role in inhibiting cell differentiation. In addition, the reduced levels of Bcl2 detected in the knockdown (b) suggested a potential role for Msi1 in preventing apoptosis. c) β-Actin was used as loading control.