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Table 1 Comparison of Environmental and Reproductive Risk Factors between Cases and Controls

From: The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor

Risk Factor

Group

Cases n (%)

Controls n (%)

OR

95% CI

P value

High Blood Pressure (yes/no)

yes

107 (56.0)

114 (39.2)

1.978

1.366 – 2.864

p < 0.001

 

no

84 (44.0)

177 (60.8)

   

Diabetes (yes/no)

yes

44 (23.0)

31 (10.7)

2.51

1.519 – 4.148

p < 0.001

 

no

147 (77.0)

260 (89.3)

   

Hormone Therapy (yes/no)

yes

47 (24.6)

40 (13.7)

2.048

1.282 – 3.273

p = 0.003

 

no

144 (75.4)

251 (86.3)

   

Alcohol consumption (ever/never)

ever

92 (48.2)

228 (78.4)

0.257

0.172 – 0.382

p < 0.001

 

never

99 (51.8)

63 (21.6)

   

BMI

<25 kg/m2

34 (19.1)

72 (24.7)

0.718

0.454–1.136

p = 0.157

 

>= 25 kg/m2

144 (80.9)

219 (75.3)

   

Smoking (ever/never)

ever

52 (27.2)

68 (23.4)

1.227

0.807 – 1.865

p = 0.338

 

never

139 (72.8)

223 (76.6)

   

Ovarian Cancer (yes/no)

yes

7 (3.7)

1 (0.3)

11.033

1.346 – 90.403

p = 0.025

 

no

184 (96.3)

290 (99.7)

   

Cervical Cancer (yes/no)

yes

8 (4.2)

2 (0.7)

6.317

1.327 – 30.077

p = 0.021

 

no

183 (95.8)

289 (99.3)

   

History of Ovarian or Cervical Cancer (yes/no)

yes

15 (7.9)

3 (1.0)

8.182

2.335 – 28.663

p = 0.001

 

no

176 (92.1)

288 (99.0)

   

Personal History of Any Cancer (yes/no)

yes

51 (26.7)

28 (9.6)

3.422

2.066 – 5.667

p < 0.001

 

no

140 (73.3)

263 (90.4)

   

History of Skin Cancer (yes/no)

yes

20 (10.5)

19 (6.5)

1.674

0.869 – 3.228

p = 0.124

 

no

171 (89.5)

272 (93.5)

   

History of Bowel Cancer (yes/no)

yes

10 (5.2)

8 (2.7)

1.954

0.757 – 5.045

p = 0.166

 

no

181 (94.8)

283 (97.3)

   
  1. Note: BMI not known for 13 cases.