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Table 2 Potential CREB target genes.

From: Expression profile of CREB knockdown in myeloid leukemia cells

Gene Name Fold Change CREB binding CREB site Gene Name Fold Change CREB binding CREB site
ACOX1 2.110674 2.911283 H ht LDLR 1.678587 1.525499 ht
ADAT1 1.410234 3.769574 ht f h LGALS3BP 2.131291 3.615437 none
APEH 1.400261 2.527266 h LIM 1.696177 1.097432 none
APPBP2 1.486616 2.151867 H ht h LIM 1.849989 1.097432 none
ARHB 2.758453 2.77377 H ht LRRFIP1 1.941595 1.122307 h
ATP6V1A 1.446867 3.016595 HT ht h METAP2 1.916632 2.635425 ht
BCL6 1.640646 6.084626 HT ht METTL2 1.593867 3.474639 none
BDKRB2 1.600927 2.601219 none MGC2731 1.588545 2.80081 HT h
BTN3A2 1.465264 3.426679 ht MGC4054 1.502743 2.777966 ht
C20orf12 1.511854 3.12999 h MOCS3 1.796255 5.213295 none
C20orf121 1.456022 3.532969 H MRPS10 1.410471 1.834794 ht f
C20orf172 1.463616 4.659037 H h NCOA3 1.495237 2.715807 ht
C20orf23 1.528396 2.622103 none NDRG1 2.030896 2.312257 ht h
CD44 9.531947 1.335178 ht h NEDF 1.567662 4.268912 ft ht
CDH12 3.296441 1.178959 none NPR2L 1.618864 6.397355 ht h
CDKAL1 1.735322 3.445022 none ODZ1 1.448279 2.310975 ht
CDKN1A 2.216725 1.778747 H ht h OPA3 1.474233 7.631458 FHT ht h
CELSR3 1.546375 3.175919 H ht OTC 1.693003 4.881484 ht
CENPF 1.415064 2.654622 ht PAFAH2 1.67217 4.584628 none
CHRNB1 1.55045 1.412576 H h PAFAH2 1.631066 4.584628 none
CLECSF2 1.747573 1.251667 none PHC3 1.42261 1.747154 ht
CML2 1.47905 3.427882 ht PHLDA1 3.92008 2.003171 h
COL15A1 2.56792 1.394566 none PLAT 1.668223 1.95203 none
CREM 1.793497 3.67068 H PLEKHB2 1.568395 4.611748 f
CRKL 1.690269 3.051845 H h PPARGC1 2.268458 2.972107 HT F ht h
CSMD1 1.647116 1.61907 ht PPFIBP1 1.852526 2.550633 ht h
CTMP 1.548763 3.386235 none PPP1R10 1.870902 2.447557 H h
DBT 1.518604 4.292329 none PPP1R3B 1.693114 1.622596 h
DCLRE1C 1.41992 3.010944 none PSMAL/GCP 1.506527 2.707076 none
DDOST 1.582101 2.508459 ht RAB7L1 1.638378 1.15364 ht h
DDX3X 1.817009 3.42975 none RABL2B 1.486054 2.496157 h
DEGS 1.488221 1.464348 none RASSF1 1.431271 4.04395 none
DIAPH1 1.412484 2.96506 none RBL1 1.529652 2.451247 h
DUSP1 1.578824 2.102797 FT HT ht h REL 1.944847 1.143935 H h
EGR2 5.148023 2.036633 HT ht h RHOBTB3 1.63057 2.813465 none
EIF5 1.422558 4.208549 ht h RIOK3 1.40951 2.008376 none
ELK1 1.405171 4.088789 ht RNASE6PL 1.561704 2.252099 ht
ENC1 1.957151 1.549567 h RNF32 1.954396 1.603905 H ht
F2R 1.804785 1.098488 ht h SAS 1.768493 7.735178 HT ht h
FAM13A1 1.780869 2.014276 none SERPINB9 2.244605 1.418097 ht h
FAT 2.00051 1.816506 F ht SFPQ 1.477265 3.428149 ht
FKBP14 1.78994 3.042488 ht SHARP 1.558516 1.078188 H ht
FLJ10781 1.463332 1.113364 ht h SLC31A1 1.491104 3.803168 FH ht
FLJ10803 1.726196 2.63943 ht SLC35E3 1.716026 1.969928 ht
FLJ11029 1.422001 3.085667 ht h SLC38A2 1.497716 1.914154 H ht
FLJ11151 2.413055 1.840398 h SLC39A6 1.477678 3.119807 h
FLJ20507 1.730068 2.922871 H ht h SMA3 1.414595 2.654203 ht
FOSL1 2.220086 1.929543 HT ht h SMARCF1 1.537978 1.046929 none
FRSB 1.423607 2.982919 ht SNAP29 1.521481 2.454502 h
FXC1 1.423019 5.02095 HT H ht SON 1.42477 4.933417 H
GALNS 1.772331 2.592543 h SPG4 1.413533 3.160161 none
GCA 1.690161 2.92801 H h SUFU 1.661693 2.275704 ht h
GTF2H3 1.593421 10.587057 H TAP1 1.435113 3.105625 H h
GYS1 1.418699 2.559154 h TIGD6 1.772719 3.636168 h
HBS1L 1.475369 3.891767 ht TIMP1 1.791155 1.848154 HT h
HIP1 1.537214 2.114631 ht h TNFRSF21 1.498482 2.635088 ht
HLA-C 1.429002 3.2916 h TP53AP1 1.527339 3.493111 ht h
HSPG2 1.708361 1.453039 none TPM4 2.201468 1.33368 H ht
ICAM1 2.20462 1.198603 ht h TRIM26 1.400065 6.12308 ht
ID1 1.521685 2.3068 FT ht TSSC3 1.879281 2.01021 H ht h
IDS 1.508286 1.1848 h TTF1 1.513382 3.461645 ht h
IER5 1.66867 2.847755 HT ht TUBA3 1.481437 2.500545 none
IL10RA 1.64246 2.830231 f U2AF1L1 2.758542 3.548509 ht
IL10RB 1.410005 1.192048 ht h U5-116KD 2.223148 2.779884 h
IL1R1 1.812093 1.329947 ht USP2 2.35423 3.920336 HT H h
IL6 1.980266 1.460112 HT ht VPS4B 1.474465 6.693871 H ht
IL6ST 1.54702 3.418269 none YME1L1 1.441837 1.843132 F ht h
INPP1 2.071508 1.550135 ht h ZFP37 1.572207 4.659572 ht h
ITGA5 2.028008 1.315131 none ZNF142 1.50914 3.028386 h
JM4 1.606813 2.392743 HT h ZNF155 1.69746 4.195939 none
KIAA0266 1.504796 2.986155 none ZNF189 1.625836 4.104303 ht h
KIF14 1.453888 4.181899 none ZNF221 1.777122 3.569536 none
KIF3B 1.623133 1.560467 none ZNF324 1.488601 4.205703 h
LCMT2 1.587221 2.338943 H ht h     
  1. Top up-regulated genes that show significant CREB binding and changes in expression in the CREB knockdown cells. The detailed criteria for selecting these genes are described in the methods section. The column descriptions are the same as in Table 1.