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Table 2 Relative risk of cancer in relation to carrier probability

From: Cancer incidence in relatives of British Fanconi Anaemia patients

  Male Female
Carrier Probability No. in Group Obs Exp O/E No. in Group Obs Exp O/E
1 33 2 1.86 1.07 31 1 1.29 0.78
0.66 13 0 0.05 0 18 0 0.90 0
0.5* 109 7 10.04 0.70 123 12 12.36 1.03
0.25 121 16 14.97 1.07 127 17 16.27 1.04
  1. *This group included 2 nephews and 2 nieces (carrier probability = 0.33), none of whom had cancer.
  2. Obs = number of cancers observed, Exp = number of cancers expected, O/E = observed cases divided by expected cases.