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Table 2 Relative risk of cancer in relation to carrier probability

From: Cancer incidence in relatives of British Fanconi Anaemia patients

 

Male

Female

Carrier Probability

No. in Group

Obs

Exp

O/E

No. in Group

Obs

Exp

O/E

1

33

2

1.86

1.07

31

1

1.29

0.78

0.66

13

0

0.05

0

18

0

0.90

0

0.5*

109

7

10.04

0.70

123

12

12.36

1.03

0.25

121

16

14.97

1.07

127

17

16.27

1.04

  1. *This group included 2 nephews and 2 nieces (carrier probability = 0.33), none of whom had cancer.
  2. Obs = number of cancers observed, Exp = number of cancers expected, O/E = observed cases divided by expected cases.