Table 3 Response to second line chemotherapy in patients with mucinous ovarian cancer with a recurrence free interval > 6 months compared to other histological subtypes
Mucinous | Other histotypes | p | |
|---|---|---|---|
N pts. | 20 | 388 | |
Type of second line chemotherapy | 19 | 384 | |
Platinum single agent | (8) 42.1% | (67) 17.4% | 0.0259* |
Platinum based combination | (6) 31.6% | (184) 47.9% | |
No platinum | (5) 26.3% | (133) 34.6% | |
Response rate to second line | |||
All evaluable patients | 11 | 340 | |
CR + PR | (4) 36.4% | (213) 62.6% | 0.0407* |
Platinum | 7 | 227 | |
CR + PR | (4) 57.1% | (170) 74.9% | n.s.* |
Non-platinum | 4 | 113 | |
CR + PR | (-) 0% | (43) 38.1% | n.s.* |
Number of chemotherapy lines received for recurrence | |||
Mean (± s.d.) | 1.9 ± 1.1 | 2.8 + 1.3 | 0.0023** |