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Table 3 Statistical comparison (Mann-Whitney analysis) of levels of HDAC expression (medians) between tumor groups.

From: Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas

 

p value

 

HDAC1

HDAC2

HDAC3

HDAC8

Glioblastoma x

    

Normal brain

ns

ns

ns

ns

AI and II

ns

ns

ns

ns

AIII

ns

ns

ns

ns

 

HDAC4

HDAC5

HDAC6

HDAC7

Glioblastoma x

    

Normal brain

<0.0001

0.018

0.011

ns

AI and II

0.012

ns

0.001

ns

AIII

0.010

ns

0.010

0.008

 

HDAC9a

HDAC9b

HDAC10

HDAC11

Glioblastoma x

    

Normal brain

0.0096

<0.0001

0.015

0.0001

AI and II

0.01

0.013

0.001

0.0003

AIII

ns

ns

ns

0.023

  1. AI, AII, and AIII mean astrocytoma grades I, II and III, respectively.
  2. ns: no significant
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BMC Cancer

ISSN: 1471-2407

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