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Table 3 Differentially expressed proteins in pancreatic juice from PDAC patients and cancer-free controls (with and without pancreatitis)

From: Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients

Spot position

Protein Name

MW(Da)

PI

Mascot PMF Score

Sequence Coverage (%)

Protein Species Score (C.I.%)

Fold change

       

PDAC/Cancer-free controls

Pancreatitis/No pancreatitis controls

1406

Alpha-1-antitrypsin precursor

46737

5.37

298

39.788

100

3.43

-1.72

1394

Serum albumin precursor

69367

5.92

491

73.493

100

2.67

-1.27

2106

Apolipoprotein A-I precursor

30778

5.56

289

56.054

100

4.83

1.30

1652

Glutathione S-transferase P

32311

5.43

90

68.249

99.998

3.84

-1.36

1312

Alpha-1B-glycoprotein precursor

54273

5.58

124

33.863

100

2.39

-1.37

1471

Vitamin D-binding protein precursor

52964

5.40

300

60.622

100

5.60

-2.03

2193

Cationic antimicrobial protein

26886

9.75

127

38.512

99.997

2.73

-3.90

2196

Superoxide dismutase [Mn], mitochondrial precursor

24722

8.35

109

36.524

100

2.54

2.12

1543

Serotransferrin precursor

77050

6.81

519

76.674

100

5.09

1.03

1971

Ig lambda chain V-IV region Hil

11517

6.04

102

49.056

100

2.66

1.44

1253

matrix metalloproteinase-9

78427

5.69

214

32.458

100

3.67

-1.03

1318

Hemopexin precursor

51676

6.55

213

42.289

100

3.23

1.06

2155

Oncogene DJ1

19891

6.33

114

15.878

100

2.59

-1.25

1739

Fibrinogen beta chain precursor

55928

8.54

247

53.067

100

4.15

-2.56

2048

Trypsin-1 precursor

26558

6.08

121

35.176

100

-2.64

2.80

1807

Carboxypeptidase A2 precursor

46828

5.68

208

52.449

100

-13.00

1.41

2007

Complement C4-B precursor

192793

6.73

123

31.488

100

-2.10

-1.50

2114

Chymotrypsinogen B precursor

27870

6.79

146

36.051

100

-2.43

1.30

2052

Elastase-3A precursor

29475

6.43

143

35.156

100

-5.71

-1.80

2030

Elastase-3B precursor

29293

5.65

157

42.945

100

-2.30

1.12

1967

Fibrinogen-like protein 1 precursor

36392

5.58

196

57.347

100

-2.71

-1.51

1857

Haptoglobin precursor

45205

6.13

163

45.013

100

-2.00

-1.72

2064

Trypsin-3 precursor

32499

7.46

120

27.118

100

-2.82

3.20

2129

Complement C3 precursor

187148

6.02

248

54.849

100

-3.78

4.04