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Table 2 CHEK2 1217G>A Frequency

From: Identification of a novel CHEK2variant and assessment of its contribution to the risk of breast cancer in French Canadian women

Group

BRCA

CTRL

P-Value

1

4.00% (1/25)*

0.00% (0/25)*

1.00

2

0.81% (1/124)*

0.00% (0/116)*

1.00

3

0.18% (1/543)

N/A

N/A

4

N/A

0.34% (22/6432)

N/A

Total

0.43% (3/692)

0.33% (22/6573)

0.73

  1. *Genotyped for 1100delC which was observed in 2.01% (3/149) of cases vs 0.7% (1/141) controls. If we compare the frequency in cases with that seen in the same neonatal controls used in this study, that were also tested for 1100delC by Zhang et al [30] (19 1100delC carriers among 6460 controls), then the difference between cases and controls is statistically significant (P = 0.01).