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Table 2 CHEK2 1217G>A Frequency

From: Identification of a novel CHEK2variant and assessment of its contribution to the risk of breast cancer in French Canadian women

Group BRCA CTRL P-Value
1 4.00% (1/25)* 0.00% (0/25)* 1.00
2 0.81% (1/124)* 0.00% (0/116)* 1.00
3 0.18% (1/543) N/A N/A
4 N/A 0.34% (22/6432) N/A
Total 0.43% (3/692) 0.33% (22/6573) 0.73
  1. *Genotyped for 1100delC which was observed in 2.01% (3/149) of cases vs 0.7% (1/141) controls. If we compare the frequency in cases with that seen in the same neonatal controls used in this study, that were also tested for 1100delC by Zhang et al [30] (19 1100delC carriers among 6460 controls), then the difference between cases and controls is statistically significant (P = 0.01).