Group | BRCA | CTRL | P-Value |
---|
1
| 4.00% (1/25)* | 0.00% (0/25)* | 1.00 |
2
| 0.81% (1/124)* | 0.00% (0/116)* | 1.00 |
3
| 0.18% (1/543) | N/A | N/A |
4
| N/A | 0.34% (22/6432) | N/A |
Total
|
0.43% (3/692)
|
0.33% (22/6573)
|
0.73
|
- *Genotyped for 1100delC which was observed in 2.01% (3/149) of cases vs 0.7% (1/141) controls. If we compare the frequency in cases with that seen in the same neonatal controls used in this study, that were also tested for 1100delC by Zhang et al [30] (19 1100delC carriers among 6460 controls), then the difference between cases and controls is statistically significant (P = 0.01).