Figure 1
From: Potential value of PTEN in predicting cetuximab response in colorectal cancer: An exploratory study
Representative sections of immunohistochemical staining patterns (original magnification × 400). 1A. EGFR strong membrane staining (+3) in neoplastic cells; 1B. EGFR negativity in neoplastic cells, while in the perineurium the expression is not altered. 1C. PTEN protein loss in neoplastic cells, whereas the inflammatory cells showed strong nuclear staining; 1D. Intense PTEN protein expression in tumor cells.