Skip to main content
Figure 2 | BMC Cancer

Figure 2

From: Divergent mechanisms underlie Smad4-mediated positive regulation of the three genes encoding the basement membrane component laminin-332 (laminin-5)

Figure 2

Transient transfections with 4 kb promoter fragments of the three genes encoding LM-332. Normalized promoter activity as analyzed in transient transfections of each three Smad4-negative and Smad4-reexpressing SW480 and BxPC3 clones and of Smad4-positive LT97 adenoma cells. Bars show the mean value with the standard error of the mean. All three promoter constructs displayed increased constitutive activities in the Smad4-positive derivatives and all of them mediated Smad4-dependent TGFβ induction.

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us