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Table 2 Characteristics Of Women With Normal Or Abnormal Follow Up Cytologic Smears Following LLETZ, Chris Hani Baragwanath Hospital, 2003 – 2006.

From: Predictors of persistent cytologic abnormalities after treatment of cervical intraepithelial neoplasia in Soweto, South Africa: a cohort study in a HIV high prevalence population

 

Abnormal*

(n = 285)

Normal*

(n = 290)

p-value

Age, mean (sd)

35.1 (8.0)

37.5 (8.9)

0.001

Parity, mean (sd)

2.7 (1.02)

2.98 (0.97)

0.004

Contraceptive method, n (%) reporting use

   

   Norethisterone oenanthate

32 (11.2)

43 (14.8)

0.200

   Depomedroxyprogesterone acetate

29 (10.2)

48 (16.6)

0.025

   Intra-uterine contraceptive device

3 (1.1)

4 (1.4)

0.721

   Progestogen-only pill

3 (1.1)

7 (2.4)

0.212

   Combined oral contraceptive

20 (7.0)

26 (9.0)

0.389

   Sterilization

9 (3.2)

19 (6.6)

0.059

HIV status, n (%) self-reporting status

  

<0.0001

   Negative

37 (13.0)

112 (38.6)

 

   Positive

184 (64.6)

82 (28.3)

 

   Unknown

64 (22.5)

96 (33.1)

 

CD4, n (%)

  

<0.0001

   <200

91 (55.5)

23 (31.1)

 

   200 – 499

59 (36.0)

33 (44.6)

 

   >499

14 (8.5)

18 (24.3)

 

On antiretroviral therapy

68 (23.86)

21 (7.24)

<0.0001

Baseline smear result, n (%)

  

0.947

   H SIL

216 (75.8)

196 (67.6)

 

   L SIL

34 (11.9)

33 (11.4)

 

   ASCUS

12 (4.2)

12 (4.1)

 

Histology of excised transformation zone, n (%)

270

255

0.139

   Normal

6 (2.2)

7 (2.8)

 

   CIN I

18 (6.8)

28 (11.3)

 

   CIN II

116 (43.9)

90 (36.3)

 

   CIN III

129 (48.9)

126 (50.8)

 

   Microinvasion

1 (0.4)

4 (1.6)

 

Presence of dysplasia at the margin of excised transformation zone

253

243

<0.0001

   Both

35 (13.8)

14 (5.8)

 

   Ectocervical

84 (33.2)

46 (18.9)

 

   Endocervical

35 (13.8)

35 (14.4)

 

   Margins clear

99 (39.1)

148 (60.9)

 
  1. * Numbers in each category may not sum to the total for the column owing to missing values.