Table 1 Patient characteristics (n 70)¹

Median Age in years (range)

Stage at Initial Diagnosis of Breast Cancer

I/II

III

IV

Hormone Receptor Status

   ER and or PgR positive

   ER and PgR Negative

   ER and PgR Unknown

Exposure to anthracycline before the initial T-based regimen³

Exposure to taxane before the initial T-based regimen³

Prior Lines of Chemotherapy for Metastatic Disease⁴

   1

   2

   ≥ 3

Initial Trastuzumab-based regimen

   Docetaxel 75–100 mg/m² q3wks + T

   Paclitaxel 80–90 mg/m² weekly +T

   Paclitaxel 175 mg/m² q3wks + T

   Vinorelbine 25–30 mg/m² weekly + T

   Docetaxel 75 mg/m² + Epi-doxorubicin 75 mg/m² q3wks + T

   T alone

   Other regimens

   Unknown

Median Number of Metastatic Sites

Pattern of Metastatic Disease

   Visceral (Liver + Lung)

   Non Visceral/Non CNS (Bone, Soft Tissue, Effusions)

   Central Nervous System (plus other sites)