Table 2 Proteolytic enzymes, CEA and CA 19-9 in correlation with Dukes classification.
| Stage | CATB | CATL | uPA | PAI-1 | CEA | CA 19-9 |
|---|---|---|---|---|---|---|
| DUKES A (n = 7) |
4.50 (2.4–37.3) |
1.10 (1.0–35.3) |
0.30 (0.2–0.62) |
32.81 (17.2–66.7) |
3.00 (0.6–3.4) |
6.80 (3.0–11.5) |
| DUKES B (n = 12) |
6.75 (3.2–23.8) |
1.00 (1.0–12.3) |
0.29 (0.1–0.79) |
39.09 (13.5–108.1) |
2.00 (0.6–21.1) |
7.65 (1.0–35.0) |
| DUKES C (n = 23) |
8.60 (3.6–35.7) |
1.10 (1.0–34.1) |
0.26 (0.1–0.79) |
52.54 (13.8–126.4) |
2.20 (0.4–235.0) |
9.20 (1.0–78.6) |
| DUKES D (n = 14) |
24.25*§ (9.2–39.3) |
4.55 (1.0–35.2) |
0.29 (0.12–0.42) |
82.03** (38.7–138.6) |
8.30# (1.9–74.6) |
35.85** (4.6–540.0) |
| Kruskall-Wallis analysis of variance (P value) | P = 0.0002 | P = NS | P = NS | P = 0.01 | P = 0.003 | P = 0.001 |