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Table 1 List of included studies utilised in indirect comparison of gemcitabine based combination chemotherapy

From: Gemcitabine based combination chemotherapy in advanced pancreatic cancer-indirect comparison

Comparison Trial Group (number randomised)
Gemcitabine versus gemcitabine plus capecitabine Cunningham 2005 (interim analyses) [12] Gemcitabine (n = 266)
Gemcitabine combination (n = 267)
  Hermann 2005 [13, 14] (analyses based on data from abstract published in 2005, plus extra data provided by trialist) Gemcitabine (n = 159)
Gemcitabine combination (n = 160)
  Scheithauer 2003 [15] Gemcitabine (n = 42)
Gemcitabine combination (n = 41)
Gemcitabine versus gemcitabine plus 5FU Berlin 2002 [8] Gemcitabine (n = 162)
Gemcitabine combination (n = 160)
  Di Costanzo 2005 [10] Gemcitabine (n = 48)
Gemcitabine combination (n = 43)
  Reiss 2005 [9] Gemcitabine (n = 236)
Gemcitabine combination (n = 230)
Gemcitabine versus gemcitabine plus platinum compound Heinemann 2006 [16] Gemcitabine (n = 99)
Gemcitabine combination (n = 96)
  Louvet 2005 [17] Gemcitabine (n = 163)
Gemcitabine combination (n = 163)
  Poplin 2006 [18] Gemcitabine (n = 280)
Gemcitabine combination (n = 276)
Gemcitabine versus gemcitabine plus irinotecan Rocha Lima 2004 [19] Gemcitabine (n = 180)
Gemcitabine combination (n = 180)
  Stathopoulos 2005 [20, 21] (analyses based on data from abstract published in 2005, plus extra data provided by trialist) Gemcitabine (n = 69)
Gemcitabine combination (n = 57)