Table 1 List of included studies utilised in indirect comparison of gemcitabine based combination chemotherapy
From: Gemcitabine based combination chemotherapy in advanced pancreatic cancer-indirect comparison
Comparison | Trial | Group (number randomised) |
|---|---|---|
Gemcitabine versus gemcitabine plus capecitabine | Cunningham 2005 (interim analyses) [12] | Gemcitabine (n = 266) Gemcitabine combination (n = 267) |
| Â | Hermann 2005 [13, 14] (analyses based on data from abstract published in 2005, plus extra data provided by trialist) | Gemcitabine (n = 159) Gemcitabine combination (n = 160) |
| Â | Scheithauer 2003 [15] | Gemcitabine (n = 42) Gemcitabine combination (n = 41) |
Gemcitabine versus gemcitabine plus 5FU | Berlin 2002 [8] | Gemcitabine (n = 162) Gemcitabine combination (n = 160) |
| Â | Di Costanzo 2005 [10] | Gemcitabine (n = 48) Gemcitabine combination (n = 43) |
| Â | Reiss 2005 [9] | Gemcitabine (n = 236) Gemcitabine combination (n = 230) |
Gemcitabine versus gemcitabine plus platinum compound | Heinemann 2006 [16] | Gemcitabine (n = 99) Gemcitabine combination (n = 96) |
| Â | Louvet 2005 [17] | Gemcitabine (n = 163) Gemcitabine combination (n = 163) |
| Â | Poplin 2006 [18] | Gemcitabine (n = 280) Gemcitabine combination (n = 276) |
Gemcitabine versus gemcitabine plus irinotecan | Rocha Lima 2004 [19] | Gemcitabine (n = 180) Gemcitabine combination (n = 180) |
| Â | Stathopoulos 2005 [20, 21] (analyses based on data from abstract published in 2005, plus extra data provided by trialist) | Gemcitabine (n = 69) Gemcitabine combination (n = 57) |