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Table 1 Growth of HME16C tumors in nude mice

From: TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation

Cell Line Innoculated Number of Mice with Tumors Mean Tumor Latency Mean Tumor Volume at Sacrifice (mm3)*
pLRT 0/10 - -
H-RasV12 10/10 4 weeks 808.8 +/- 635.2
H-RasV12G37 0/10 - -
H-RasV12S35 5/10 12 weeks 109.0 +/- 171.0
H-RasV12C40 0/10 - -
Rlf-CAAX 0/10 - -
  1. Cells infected with control, Ras-expressing, or Rlf-CAAX-expressing retrovirus were injected subcutaneously into nude mice and examined for tumor formation and growth. *For mice injected with H-RasV12S35 cells, includes only sites that formed tumors.