TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation

BMC Cancer

Table 1 Growth of HME16C tumors in nude mice

Cell Line Innoculated	Number of Mice with Tumors	Mean Tumor Latency	Mean Tumor Volume at Sacrifice (mm³)*
pLRT	0/10	-	-
H-Ras^V12	10/10	4 weeks	808.8 +/- 635.2
H-Ras^V12G37	0/10	-	-
H-Ras^V12S35	5/10	12 weeks	109.0 +/- 171.0
H-Ras^V12C40	0/10	-	-
Rlf-CAAX	0/10	-	-

Cells infected with control, Ras-expressing, or Rlf-CAAX-expressing retrovirus were injected subcutaneously into nude mice and examined for tumor formation and growth. *For mice injected with H-Ras^V12S35 cells, includes only sites that formed tumors.

ISSN: 1471-2407