|
Cell Line Innoculated
|
Number of Mice with Tumors
|
Mean Tumor Latency
|
Mean Tumor Volume at Sacrifice (mm3)*
|
|---|
|
pLRT
|
0/10
|
-
|
-
|
|
H-RasV12
|
10/10
|
4 weeks
|
808.8 +/- 635.2
|
|
H-RasV12G37
|
0/10
|
-
|
-
|
|
H-RasV12S35
|
5/10
|
12 weeks
|
109.0 +/- 171.0
|
|
H-RasV12C40
|
0/10
|
-
|
-
|
|
Rlf-CAAX
|
0/10
|
-
|
-
|
- Cells infected with control, Ras-expressing, or Rlf-CAAX-expressing retrovirus were injected subcutaneously into nude mice and examined for tumor formation and growth. *For mice injected with H-RasV12S35 cells, includes only sites that formed tumors.
