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Table 3 Results of Cox proportional hazard regression analysis

From: Clinical implications of thymidylate synthetase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activity levels in colorectal carcinoma following radical resection and administration of adjuvant 5-FU chemotherapy

Prognostic factors

P

Hazards ratio

Age (69 < vs. > 70)

0.28

0.18

Sex (male vs. female)

0.67

0.015

TS activity (high vs. low)

0.05

3.85

DPD activity (high vs. low)

0.90

0.06

OPRT activity (high vs. low)

0.03

5.04

Tumor size (< 4.9 vs. > 5.0 cm)

0.80

0.03

Lymphnode metastasis

0.15

1.36

(absent vs. present)

  

Histology (well vs. mod)

0.90

0.01

Tumor depth (ss vs. se)

0.18

1.20

  1. s.s.: histological tumor invasion of subserosa, s.e.:histological tumor invasion of serosa. Well: well differentiated adenocarcinoma, mod: moderately differentiated adenocarcinoma.
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BMC Cancer

ISSN: 1471-2407

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