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Figure 1 | BMC Cancer

Figure 1

From: Chrysotile effects on human lung cell carcinoma in culture: 3-D reconstruction and DNA quantification by image analysis

Figure 1

HK2 cells in control situation and after 48 h chrysotile exposure. Confocal images of HK2 cells, showing microtubules (green) and DNA stained by PI (red). A) Control HK2 cells were predominantly mononucleated and apoptosis were rarely observed. B and C) HK2 cells after treatment with chrysotile for 48 h and additional 24 h in fiber-free medium show high frequency of multinucleated cells (arrows) and apoptosis (arrows tips). The pattern of microtubules in interphasic treated cells is similar to control cells, however in multinucleated cells a reorganization of cytoskeleton in a radiated distribution was observed.

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BMC Cancer

ISSN: 1471-2407

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