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Table 4 Sensitivity of A2780 and A2780cis cells to cisplatin and CFDA-Pt.

From: Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells

 

A2780

A2780cis

 
 

pEC50

EC50, μM

pEC50

EC50, μM

p

cisplatin

5.455 ± 0.0941

3.5

4.631 ± 0.0095

23.4

0.0001

CFDA-Pt

4.445 ± 0.1524

35.9

3.856 ± 0.0711

139.3

0.0127

  1. Sensitivity of A2780 and A2780cis cells to cisplatin and CFDA-Pt was assessed using an MTT-based assay. The pEC50 values are means ± SE of four experiments. The significance of differences was analysed using Student's t test.
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BMC Cancer

ISSN: 1471-2407

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