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Table 4 Sensitivity of A2780 and A2780cis cells to cisplatin and CFDA-Pt.

From: Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells

  A2780 A2780cis  
  pEC50 EC50, μM pEC50 EC50, μM p
cisplatin 5.455 ± 0.0941 3.5 4.631 ± 0.0095 23.4 0.0001
CFDA-Pt 4.445 ± 0.1524 35.9 3.856 ± 0.0711 139.3 0.0127
  1. Sensitivity of A2780 and A2780cis cells to cisplatin and CFDA-Pt was assessed using an MTT-based assay. The pEC50 values are means ± SE of four experiments. The significance of differences was analysed using Student's t test.