Figure 2From: CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23 Representative examples of CADM1 mRNA expression in cell lines untreated (0) or treated with 5-aza-2'-deoxycytidine (DAC). Cell lines NMB, NLF and CHP-134 show a more than 2-fold upregulation of CADM1 expression after treatment with DAC. CADM1 copy number status is indicated: NB cell lines GI-C-IN and CHP-134 show no loss of the CADM1 locus as determined by array CGH, while in NMB and NLF loss of CADM1 was observed. All cell lines were unmethylated following bisulphite sequencing. Lowest expression is rescaled to 1.Back to article page