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Table 4 Survival analysis from birth, BRCA1 and BRCA2 combined for each birth cohort, index case excluded

From: Penetrance estimates for BRCA1 and BRCA2based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

% died from birth to age <1900 (n = 45) 1900–1919 (n = 154) 1920–1929 (n = 154) 1930–1939 (n = 124) 1940–1949 (n = 158) 1950–1959 (n = 162) 1960+ (n = 276)
45 years 15% 14% 17% 17% 21% 15% 17%
60 years 42% 56% 57% 62% 56%   
70 years 73% 74% 77% 85%    
  1. Log Rank 11.53 df6 p = 0.07