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Table 4 Survival analysis from birth, BRCA1 and BRCA2 combined for each birth cohort, index case excluded

From: Penetrance estimates for BRCA1 and BRCA2based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

% died from birth to age

<1900 (n = 45)

1900–1919 (n = 154)

1920–1929 (n = 154)

1930–1939 (n = 124)

1940–1949 (n = 158)

1950–1959 (n = 162)

1960+ (n = 276)

45 years

15%

14%

17%

17%

21%

15%

17%

60 years

42%

56%

57%

62%

56%

  

70 years

73%

74%

77%

85%

   
  1. Log Rank 11.53 df6 p = 0.07