From: Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas
 | Apoptosis1 |  |  |  |  |
---|---|---|---|---|---|
Plasma IGFBP-3 | Lower Half/Upper Half (n) | Unadjusted OR (95% CI)2 | P | Adjusted OR (95% CI)2,3 | P |
Quartile 4 | 59/44 | 1.0 (Reference) | -- | 1.0 (Reference) | -- |
Quartile 3 | 57/44 | 1.0 (0.6, 0.7) | 0.90 | 1.0 (0.6, 0.7) | 0.90 |
Quartile 2 | 58/45 | 1.0 (0.6, 0.7) | 0.89 | 1.0 (0.6, 0.7) | 0.89 |
Quartile 1 | 58/50 | 0.9 (0.5, 1.5) | 0.60 | 0.9 (0.5, 1.5) | 0.60 |
P for linear trend | Â | Â | 0.70 | Â | 0.70 |
Colonic tissue IGFBP-3 | Lower Half/Upper Half (n) | Unadjusted OR (95% CI)2 | P | Adjusted OR (95% CI)2,4 | P |
Quartile 4 | 63/43 | 1.0 (Reference) | -- | 1.0 (Reference) | -- |
Quartile 3 | 62/51 | 0.8 (0.5, 1.4) | 0.50 | 0.6 (0.3, 1.1) | 0.12 |
Quartile 2 | 64/43 | 1.0 (0.6, 1.8) | 0.96 | 0.8 (0.5, 1.5) | 0.57 |
Quartile 1 | 51/70 | 0.5 (0.3, 0.8) | 0.01 | 0.5 (0.3, 0.8) | 0.009 |
P for linear trend | Â | Â | 0.10 | Â | 0.04 |