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Table 4 Odds ratio and 95% CI for the association between plasma IGFBP-3 or colonic tissue IGFBP-3 and apoptosis

From: Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas

  Apoptosis1     
Plasma IGFBP-3 Lower Half/Upper Half (n) Unadjusted OR (95% CI)2 P Adjusted OR (95% CI)2,3 P
Quartile 4 59/44 1.0 (Reference) -- 1.0 (Reference) --
Quartile 3 57/44 1.0 (0.6, 0.7) 0.90 1.0 (0.6, 0.7) 0.90
Quartile 2 58/45 1.0 (0.6, 0.7) 0.89 1.0 (0.6, 0.7) 0.89
Quartile 1 58/50 0.9 (0.5, 1.5) 0.60 0.9 (0.5, 1.5) 0.60
P for linear trend    0.70   0.70
Colonic tissue IGFBP-3 Lower Half/Upper Half (n) Unadjusted OR (95% CI)2 P Adjusted OR (95% CI)2,4 P
Quartile 4 63/43 1.0 (Reference) -- 1.0 (Reference) --
Quartile 3 62/51 0.8 (0.5, 1.4) 0.50 0.6 (0.3, 1.1) 0.12
Quartile 2 64/43 1.0 (0.6, 1.8) 0.96 0.8 (0.5, 1.5) 0.57
Quartile 1 51/70 0.5 (0.3, 0.8) 0.01 0.5 (0.3, 0.8) 0.009
P for linear trend    0.10   0.04
  1. 1 Number of subjects in each quartile that fall in the lower half or upper of apoptosis
  2. 2 Odds ratio (OR) and 95% confidence interval (CI), odds of being in the lower 50th percentile of apoptosis.
  3. 3 No potential confounders remained in the final model for Plasma IGFBP-3.
  4. 4 Adjusted for red meat for Tissue IGFBP-3.