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Figure 2 | BMC Cancer

Figure 2

From: High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies

Figure 2

Difference plots and sequence traces for EGFR exons 18 and 19. Panel A: The difference plot of EGFR exon 18 shows melting profiles for three positive samples (TX36 in purple, TX53 in orange and TX290 in red). Panel B: Sequencing chromatograms show a p.E709A in TX36, a p.G719S in TX53 and a p.E709_T710delinsD in TX290. Panel C: The difference plot of EGFR exon 19 shows melting profiles for three positive samples (TX127 in brown, TX142 in red and TX186 in orange). Panel D: Sequencing chromatograms show a p.L747_P753delinsS in TX127, a p.E746_A750del in TX142 and a p.E746_A750delinsF mutation in TX186.

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BMC Cancer

ISSN: 1471-2407

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