Figure 1
From: Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis
Effects of TFIIS siRNA on Cell Proliferation. MCF7 and MCF10A cell lines were subjected to siRNA directed at TFIIS as listed in Table 1, scrambled siRNA (S-siRNA) or Eg5 and MTS values determined 72 hours after transfection. Cell proliferation represents the fraction of viable cells compared to cells transfected with vehicle alone (1 = 100% viable cells when treated with vehicle alone). Standard error of the mean is indicated as bars in the figure. Caspase-3/7 activity is also depicted and normalized to cell number represented by MTS values. Total activity was then normalized to activity in cells treated with vehicle alone.