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Figure 4 | BMC Cancer

Figure 4

From: Expression of HER-2 in MCF-7 breast cancer cells modulates anti-apoptotic proteins Survivin and Bcl-2 via the extracellular signal-related kinase (ERK) and phosphoinositide-3 kinase (PI3K) signalling pathways

Figure 4

Bcl-2 is up-regulated in HER-2 expressing MCF7 cell line: pTRE-HER2 and pTRE-transfected MCF-7 clones were incubated with or without doxycycline for 48 hours. Whole cell protein extracts were collected and analyzed for expression of Bcl-2 by western blotting.

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