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Table 3 Enriched GO terms in the category "Biological Process" among the significantly differentially expressed genes.

From: Cross-study analysis of gene expression data for intermediate neuroblastoma identifies two biological subtypes

GO term Expression Count {55} Total {857} p-value Corrected p
base-excision repair - 2 2 0.004 0.307
regulation of kinase activity + 5 19 0.005 0.307
regulation of protein kinase activity + 5 19 0.005 0.307
regulation of transferase activity + 5 20 0.007 0.307
negative regulation of transferase activity + 3 7 0.007 0.307
negative regulation of protein kinase activity + 3 7 0.007 0.307
negative regulation of enzyme activity + 3 8 0.011 0.361
regulation of enzyme activity + 5 25 0.018 0.361
response to DNA damage stimulus - 4 17 0.019 0.361
response to endogenous stimulus - 4 17 0.019 0.361
MAPKKK cascade + 3 10 0.022 0.361
one-carbon compound metabolism - 2 4 0.022 0.361
negative regulation of MAPK activity + 2 4 0.022 0.361
inactivation of MAPK activity + 2 4 0.022 0.361
M phase of mitotic cell cycle - 4 18 0.024 0.361
phosphorus metabolism + 9 68 0.033 0.361
phosphate metabolism + 9 68 0.033 0.361
M phase - 4 20 0.034 0.361
regulation of cyclin dependent protein kinase activity - 2 5 0.036 0.361
glycolysis - 2 5 0.036 0.361
Wnt receptor signaling pathway + 2 5 0.036 0.361
oxidative phosphorylation * 2 5 0.036 0.361
  1. Expression: expression of associated genes in tumors with a favourable prognosis relative to the expression in tumors with unfavourable prognosis; +: up-regulation; -: down-regulation; *: genes show oppositional expression.
  2. Count: number of significant genes associated with given GO term. Total: number of genes in analysis associated with given GO term. The numbers in curly brackets denote the number of genes that could be mapped to GO. Corrected p-values were calculated according to Benjamini and Hochberg as implemented in GOstat.