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Table 2 List of differentially expressed genes.

From: Cross-study analysis of gene expression data for intermediate neuroblastoma identifies two biological subtypes

Symbol

Name

z score

only found in M.A.

NDUFV1

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51 kDa

-3.98

 

TP53

Tumor protein p53 (Li-Fraumeni syndrome)

-3.54

 

AHCY

S-adenosylhomocysteine hydrolase

-3.44

 

NPM1

Nucleophosmin (nucleolar phosphoprotein B23, numatrin)

-3.38

*

CHD1L

Chromodomain helicase DNA binding protein 1-like

-3.26

 

CCNB1

Cyclin B1

-3.22

 

HSPA5

Heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa)

-3.20

 

SF4

Splicing factor 4

-3.19

 

CCNA2

Cyclin A2

-3.15

 

RPS13

Ribosomal protein S13

-3.14

*

E2F1

E2F transcription factor 1

-3.12

 

FLJ11806

Nuclear protein UKp68

-3.12

 

RUVBL1

RuvB-like 1 (E. coli)

-3.10

 

CCT5

Chaperonin containing TCP1, subunit 5 (epsilon)

-3.05

*

CCT3

Chaperonin containing TCP1, subunit 3 (gamma)

-3.02

 

DDX49

DEAD (Asp-Glu-Ala-Asp) box polypeptide 49

-2.89

*

EIF2S1

Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

-2.88

 

KIFC1

Kinesin family member C1

-2.88

*

FLJ13910

Hypothetical protein FLJ13910

-2.85

 

APEX1

APEX nuclease (multifunctional DNA repair enzyme) 1

-2.83

 

COPB

Coatomer protein complex, subunit beta

-2.83

 

CDC25B

Cell division cycle 25B

-2.81

*

TMED2

transmembrane emp24 domain trafficking protein 2

-2.73

 

AHCYL1

S-adenosylhomocysteine hydrolase-like 1

-2.71

*

RAD23A

RAD23 homolog A (S. cerevisiae)

-2.70

*

HMGB2

High-mobility group box 2

-2.67

 

TRIM28

Tripartite motif-containing 28

-2.64

*

ENO1

Enolase 1, (alpha)

-2.62

*

MRPL3

Mitochondrial ribosomal protein L3

-2.61

*

MARK2

MAP/microtubule affinity-regulating kinase 2

-2.61

*

DDX1

DEAD (Asp-Glu-Ala-Asp) box polypeptide 1

-2.59

*

KIF22

Kinesin family member 22

-2.57

 

MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

2.57

*

YWHAE

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein

2.58

 

DUSP16

Dual specificity phosphatase 16

2.62

*

EZH1

Enhancer of zeste homolog 1 (Drosophila)

2.63

*

NCAM1

Neural cell adhesion molecule 1

2.63

*

MAP2K4

Mitogen-activated protein kinase kinase 4

2.64

 

ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

2.65

*

RBMS3

RNA binding motif, single stranded interacting protein

2.65

*

PXK

PX domain containing serine/threonine kinase

2.66

*

PMSCL2

Exosome component 10

2.67

*

NTRK1

Neurotrophic tyrosine kinase, receptor, type 1

2.67

*

DOCK4

Dedicator of cytokinesis 4

2.70

*

AB051522

DIX domain containing 1

2.70

*

RAB2

RAB2, member RAS oncogene family

2.70

*

FOXP1

Forkhead box P1

2.74

*

GPS2

G protein pathway suppressor 2

2.79

*

MLL5

Myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

2.82

 

DLG4

Discs, large homolog 4 (Drosophila)

2.84

*

VAMP2

Vesicle-associated membrane protein 2 (synaptobrevin 2)

2.85

 

NXPH1

Neurexophilin 1

2.89

*

ATP6V1A

ATPase, H+ transporting, lysosomal 70 kDa, V1 subunit A

2.91

 

ZNF218

zinc finger protein 218

2.93

 

FLJ13110

Receptor accessory protein 1

2.94

 

CDK5R1

Cyclin-dependent kinase 5, regulatory subunit 1 (p35)

2.96

*

NCOA7

nuclear receptor coactivator 7

2.96

*

FLJ11730

Chromosome 1 open reading frame 149

3.04

*

MARCKS

Myristoylated alanine-rich protein kinase C substrate

3.06

*

CLSTN3

Calsyntenin 3

3.08

 

CAMTA1

Calmodulin binding transcription activator 1

3.10

 

SCN3B

sodium channel, voltage-gated, type III, beta

3.11

*

PTN

Pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)

3.14

 

EPS15

Epidermal growth factor receptor pathway substrate 15

3.26

 

BRUNOL4

Bruno-like 4, RNA binding protein (Drosophila)

3.26

 

DCAMKL1

Doublecortin and CaM kinase-like 1

3.30

 

ALS2CL

ALS2 C-terminal like

3.38

 

LOC284244

Hypothetical protein LOC284244

3.41

 

RAPGEF6

Rap guanine nucleotide exchange factor (GEF) 6

3.42

 

PKIB

Protein kinase (cAMP-dependent, catalytic) inhibitor beta

3.50

 

LOC116236

Hypothetical protein LOC116236

3.89

 

FYN

FYN oncogene related to SRC, FGR, YES

3.96

 
  1. Column 'only found in M.A.': Those genes are marked that were exclusively identified by meta-analysis. A negative z-score indicates down-regulation of a gene in tumors with a favourable prognosis relative to the expression in tumors with unfavourable prognosis.
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BMC Cancer

ISSN: 1471-2407

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