Table 4 Stratification analyses for associations between rs3731055 genotypes and risk of lung cancer by selected variables

Total

541 (0.56)

426 (0.44)

512 (0.52)

473 (0.48)

1.00

0.82 (0.68–0.99)*

Age (years)

   ≤ 60

282 (0.59)

195 (0.41)

240 (0.49)

245 (0.51)

1.00

0.65 (0.50–0.85)**

   > 60

259 (0.53)

231 (0.47)

272 (0.54)

228 (0.46)

1.00

1.03 (0.80–1.34)

Sex

   Male

420 (0.56)

329 (0.44)

382 (0.52)

353 (0.48)

1.00

0.82 (0.66–1.01)

   Female

121 (0.55)

97 (0.45)

130 (0.52)

120 (0.48)

1.00

0.86 (0.59–1.24)

Smoke status

   None-smoker

178 (0.60)

119 (0.40)

251 (0.53)

221 (0.47)

1.00

0.74 (0.55–0.99)*

   Smoker

363 (0.54)

307 (0.46)

261 (0.51)

252 (0.49)

1.00

0.90 (0.71–1.13)

< 30 pack-years

136 (0.56)

107 (0.44)

136 (0.52)

127 (0.48)

1.00

0.88 (0.61–1.25)

≥ 30 pack-years

227 (0.53)

200 (0.47)

125 (0.50)

125 (0.50)

1.00

0.91 (0.66–1.24)

Family history of cancer

   No

435 (0.54)

363 (0.46)

442 (0.52)

416 (0.48)

1.00

0.84 (0.69–1.03)

   Yes

106 (0.63)

63 (0.37)

70 (0.55)

57 (0.45)

1.00

0.71 (0.43–1.18)