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Table 3 Associations between frequencies of inferred XPC haplotypes and risk of lung cancer

From: Sequence variations in DNA repair gene XPCis associated with lung cancer risk in a Chinese population: a case-control study

     Histologic types of lung cancer
XPC haplotypesa Controls Cases Adenocarcinomas Squamous cell Small cell
   n (%) OR (95% CI) n (%) OR (95% CI) n (%) OR (95% CI) n (%) OR (95% CI)
All subjects 2022 2020   860   670   130  
   GCCCC 721 (35.6) 737 (36.5) 1.00 328 (38.1) 1.00 243 (36.3) 1.00 35 (26.9) 1.00
   GCCTA 615 (30.5) 625 (30.9) 0.99 (0.85–1.16) 278 (32.3) 0.99 (0.82–1.21) 208 (31.0) 1.00 (0.81–1.24) 42 (32.3) 1.41 (0.89–2.23)
   ACCCA 453 (22.7) 414 (20.5) 0.89 (0.76–1.06) 160 (18.6) 0.78 (0.62–0.97)* 153 (22.8) 1.00 (0.79–1.27) 37 (28.5) 1.68 (1.04–2.71)*
   ACGCA 100 (4.6) 90 (4.4) 0.88 (0.65–1.19) 36 (4.2) 0.79 (0.53–1.18) 24 (3.6) 0.71 (0.45–1.14) 7 (5.4) 1.44 (0.62–3.33)
   GGGCA 74 (3.7) 78 (3.9) 1.03 (0.74–1.44) 33 (3.8) 0.98 (0.64–1.51) 22 (3.3) 0.88 (0.54–1.45) 6 (4.6) 1.67 (0.68–4.10)
   GCGCC 18 (0.9) 28 (1.4) 1.52 (0.83–2.78) 11 (1.3) 1.34 (0.63–2.88) 7 (1.0) 1.15 (0.48–2.80) 0 (0.0) ---
   Others b 41 (2.0) 48 (2.4) 1.15 (0.75–1.76) 14 (1.6) 0.75 (0.40–1.40) 13 (1.9) 0.94 (0.50–1.78) 3 (2.3) 1.51 (0.44–5.11)
  1. a Polymorphic bases were listed in the 5' to 3' order.
  2. b Others including the haplotypes with frequencies of less than 1%.
  3. *P < 0.05a