Skip to main content

Table 1 Genotype and allele frequencies of the IL-8 251 A/T and TLR-299 and -399 loci in the non-cancer and cancer groups according to histological findings

From: Assessment of the toll-like receptor 4 Asp299Gly, Thr399Ile and interleukin-8 -251 polymorphisms in the risk for the development of distal gastric cancer

 

IL8-251 A/T

TLR4 Asp299Gly

TLR4Thr399Ile

Group (n)

genotype

allele

genotype

allele

genotype

allele

 

AA

AT

TT

*A

*T

1,1

1,2

*1

*2

1,1

1,2

*1

*2

Gastritis (207)

42

97

68

0.44

0.56

190

17

0.96

0.04

196

11

0.97

0.03

PUD (29)

4

14

11

0.38

0.62

29

0

1

0

27

2

0.97

0.03

AG + IM (23)

5

10

8

0.43

0.57

20

3

0.93

0.07

23

0

1

0

Gastric cancer (78)

16

47

15

0.51

0.49

72

6

0.96

0.04

77

1

0.99

0.01

diffuse type

8

26

8

0.5

0.5

38

4

0.95

0.05

41

1

0.99

0.01

intestinal type

8

21

7

0.51

0.49

34

2

0.97

0.03

36

0

1

0

H. pylori + (191)

37

90

64

0.43

0.57

175

16

0.96

0.04

181

10

0.97

0.03

Age and gender matched (n = 189)

33

87

69

0.4

0.6

175

14

0.96

0.04

179

10

0.97

0.03

  1. PUD: peptic ulcer disease; AG, atrophic gastritis; IM: intestinal metaplasia
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us