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Table 3 Risk of epithelial ovarian cancer and SHBG-ATP1B2 extended haploptypes, among 264 ovarian cancer cases and 625 controls in the Polish Ovarian Cancer Study

From: Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study

         Haplotype frequency OR 95%CI P
Haplotypes* Cases Controls    
A T A C C C C G 0.26 0.20 1.00 (reference**)  
G . . . . . . . 0.32 0.35 0.77 0.58 – 1.01 0.06
. . . . . . G A 0.01 0.02 0.43 0.14 – 1.33 0.14
. . . T . . G . 0.12 0.11 0.89 0.60 – 1.33 0.58
. . . T . T G A 0.09 0.09 0.83 0.56 – 1.23 0.36
. . . T T T G A 0.04 0.03 1.22 0.70 – 2.12 0.49
. . G T . . G A 0.05 0.05 0.81 0.50 – 1.30 0.38
. C . T . . G . 0.07 0.07 0.81 0.53 – 1.25 0.34
G . . . . . G . 0.01 0.02 0.51 0.17 – 1.58 0.24
Global p = 0.42
  1. * Polymorphic bases in 5' to 3' order: SHBG (rs1799941, rs6257, rs6259, rs727428, rs1641544); ATP1B2 (rs16441537, rs1624085, rs1641512). Two ATP1B2 SNPs (rs1641536 and rs1641535) highly correlated (r2 > 0.98) with rs1641537 are not included in the analyses.
  2. ** The reference