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Figure 1 | BMC Cancer

Figure 1

From: A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer

Figure 1

Haplotype analysis in a HNPCC family segregating the MLH1 Pro350fs mutation. The haplotypes were constructed in SimWalk2 and subsequently visualized with HaploPainter [39]. CRC:55, colorectal cancer diagnosed at age 55; Endo, endometrial cancer; Skin, skin cancer; P, polyps; Pro350fs, carrier of the Pro350fs mutation in MLH1; wt, non-carrier; black dot, DNA of this family member has been typed on a 10K SNP array.

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